Ypaf Researchers Identify Novel Type of Antibody that Potently Inhibits HIV Infection President Azad Jammu and Kashmir Sardar Masood Khan says the demand made by British House of Commons for resolving the Kashm ir issue according to the aspirations of Kashmiris is a diplomatic achievement of the Kashmiri people. Talking to a delegation of Self-Determination Movement led by Raja Najabat Husain in Islamabad today, he said debate on the Kashmir issue at the House of Commons also proved that India is speedily moving toward isolation on this core issue. Masood Khan said the House of commons also urged India to stop its atrocities in occupied Kashmir. Masood Khan said the international community will have to its play due role to resolve this lingering dispute.Published in The Express Tribune, February 19th, 2017 . A drug candidate developed by researchers at the NIH's National Center for Advancing Translational Sciences (NCATS) and its collaborators to treat sickle cell disease has been acquired by Baxter International's BioScience business.The drug candidate, Aes-103, is the first specifically developed to target the underlying molecular mechanism of sickle cell disease. Baxter now will advance the clinical development activities required for regulatory approval and commercia lization.Sickle cell disease is a genetic blood disorder that affects millions w orldwide, including approximately 100,000 people in the United States - among them, 1 in 500 African-Americans.This is the first time a company has acquired a drug candidate developed with NCATS' Therapeutics for Rare and Neglected Diseases (TRND) program resources. Baxter International recently acquired AesRx, LLC, Newton, Massachusetts - the TRND program collaborator - including Aes-103. TRND and AesRx researchers worked together to develop Ae
Akze 'Zero recovery' for corals in back-to-back Australia bleaching Legendary rock band Black Sabbath has marked the 2016 tour as its last ever. The group’s farewell US tour shows will take place on November 8 in Tulsa, Oklahoma, November 10 in Houston, Texas and November 12 in San Antonio, Texas, reported Rolling Stone.After November 12, the band will head to Latin America for seven more dates sprea d across Mexico, Chile, Argentina and Brazil. The group’s final show is set f or Sao Paulo, Brazil on December 4.“It doesn’t get any easier, physically,” singer Ozzy Osbourne said about ‘The End’ tour. Osbourne said that touring was taking a toll on the members’ health. “I don’t know how the Stones <band> do it,” he added.German music festival halted after lightning strikes injure 71In January this year, Osbourne contracted a sinus infection that forced Black Sabbath to postpone several concerts. “This time, we thought we got one more tour left in us — let’s go out and do it while we can,” said bassist Geezer Butler. “We’re all aware of our mortality these d Abstract We present the constructio n of the lab-on-a-chip (LOC) system, a state-of-the-art technology that uses polymer materials (i.e., poly<dimethylsiloxane>) for the miniaturization of conventional laboratory apparatuses, and show the potential use of these microfluidic devices in clinical applications. In particular, we introduce the independent unit components of the LOC system and demonstrate how each component can be functionally integrated into one monolithic system for the realization of a LOC system. In specific, we demonstrate microscale polymerase chain reaction with the use of a single heater, a microscale sample injection device with a disposable plastic syringe and a strategy for device assembly under environmentally mild conditions assisted by surface modification techniques. In this way, we endeavor to construct a totally integrated, disposable microfluidic system operated by a single mode, the pressure, which can be applied on-site with enhanced device portability and
Cknk Zebrafish Produce Their Own Sunscreen SEOUL:US bombers carried out a rare live fire drill in South Korea Saturday, flying close to the DMZ in a show of force after Pyongyang's latest missile test, the South's defence ministry said.After the drill, th e B-1B Lancers, deployed from the Anderson Air Base in Guam, flew close to the tense and heavily militarised land border with the North before turning back, the Yonhap news agency reporte d.North Korea’s nuclear conundrum and Asian securityThe exercise aimed to "sternly respond to the series of North Korea's ballistic missile launches," the South's military said in a statement.Four US and South Korean jet fighters joined the live fire drill, which was conducted at a range in Yeongwol County, some 80 kilometres (50 miles) south of the inter-Korean border, the military said.The long-range heavy aircraft each dropped a 2,000-pound (907.1 kilos) laser-guided bunker-busting smart bomb.The drill simulated the two US bombers destroying enemy ballistic missile batteries and South Korean An international research team has retraced the astonishing lifetime journey of an Arctic woolly mammoth, which covered enough of the Alaska landscape during its 28 years to almost circle the Earth twice.Scientists gathered unprecedented details of its life thr ough analysis of a 17,000-year-old fossil from the University of Alaska Museum of the North. By generating and studyin g isotopic data in the mammoth’s tusk, they were able to match its movements and diet with isotopic maps of the region.Few details have been known about the lives and movements of woolly mammoths, and the study offers the first evidence that they traveled vast distances. An outline of the mammoth’s life is detailed in the new issue of the journal Science.“It’s not clear-cut if it was a seasonal migrator, but it covered some serious ground,” said University of Alaska Fairbanks researcher Matthew Wooller, senior and co-lead author of the paper. “It visited many parts of Alaska at some point during its lifetime, whic
Hfun How Giant Spider Venom Might Help Sufferers of Irritable Bowel Syndrome Indian Foreign Minister Sushma Swaraj on Monday vowed to 'personally' take up the case of a Pakistani migrant girl debarred from taking a pre-medical test in Indian."Mashal - Don't be disappointed my child. I will personally take up your case for admission in a medical college," Swaraj tweeted.Mashal - Don't be disappointed my child. I will personally take up your case for admission in a Medical College. @aajtak— Sushma Swaraj (@SushmaSwaraj) May 29, 2016Mashal, a 17-year-old Hindu girl of Pakistani origin, was precluded from taking the all-India pre-medical test because of her status as a foreigner.Pakistani migrant debarred from taking medical test in IndiaMashal’s parents moved to Jaipur from Pakistan almost two years ago to avoid alleged relig ious persecution, as well as to see their daughter become a doctor.Rewarded for her efforts, Mashal scored 91 per cent on her Central Board of Seconday Education examination s. However, the joy and celebrations of the family were shor Berg and the Icahn School of Medicine at Mount Sinai announced today a pharmaceutical and diagnostic R&D partnership that will leverage the power of multi-omic biology and data analytics to obtain novel insights and potential therapeutics for cancer, central nervous system and endocrine disorders. Over the course of this five-year partnership, Berg will leverage its award-winning Interrogative Biology™ platform in combination with Mount Sinai’s expertise in big data, advanced analytics and biological network modeling.Berg and Mount Sinai will adopt an innovative risk and return sharing approach, with downstream royalties significantly higher than the industry standard for academia-pharma partnerships. "The partnership with Mount Sinai flips the traditional public-private partnership model and sets a new standard for pharmaceutical research and development," said Niven R. Narain, Co-Founder, President and CTO of Berg. "Innovation in the healthcare industry extends far beyond sc ienti
Qhif Zika infection may affect adult brain cells S haan and Ali Azmat are two major pillars of the Pakistani entertainment industry. If one has become synonymous with Pakistani cinema, the other led a rock and roll revolution that was not just restricted to Pakistan. And both have been out of scene for quite some it. Shaan hasn't graced the big screen since Operation 02 1 and Azmat has been so caught up with his family that new music is nowhere in the sight.However, a recent picture of the two stars sitting together in a studio has our hearts racing. Where Shaan can be seen staring at what could possibly be a screen, Azmat with his headphones on also has his eyes fixed on it.Well, don't get too excited. It's not a new song that Azmat has sung and Shaan has performed on, its a picture from the ADR, (Automated Dialogue Replacement) popularly known as dubbing, session of Arth 2. . מנא מנא תקל ופרסין .com/p/BO7n3NghnXo/?taken-by=official.shaanshahidAccording to sources, Azmat will be making a cameo appearance in the film that also stars H Scientists at Scripps Research have unveiled a new Ebola virus vaccine design, which they say has several advantages over standard vaccine approaches for Ebola and related viruses that continue to threaten global health.In the new design, described in a paper inNature Communications, copies of the Ebola virus outer spike protein, known as the glycoprotein, are tether ed to the surface of a spherical carrier particle. The resulting structure resembles the spherical appearance of common RNA viruses that infect humans—and is starkly different from the snake-like shape of the Ebola virus.The scientists say the design is intended to stimulate a better protective immune response than standard vaccine approaches, which often expose the immune system to individual glycoproteins rather than realistic -looking virus particles.In designing the vaccine, the researchers also modified the outer spike protein to be more stable than the normal, “wild-type” version found in actual Ebol a virus. In tests i
Wvnw Apple chief Tim Cook meets Indian PM Modi ORANGE, UNITED STATES:Emergency workers in storm-hit southeast Texas on Thursday staged dramatic rescues by air and water in towns that were until now cut off by raging floodwaters unleashed by monster storm Harvey, which finally started to move inland.Nearly a week after the storm smashed into the US Gulf Coast as a Category Four hurricane, thousands of rescuers and civilians eager to help battled difficult conditions to reach victims of the unprecedented flooding."We felt we'd be alright. We were wrong," said Lonnie Givens, who refused to evacuate their one-story home in the town of Orange. Now, he and wife Missy have a bout four inches of water in the house and no power. "We really got nowhere to go," Givens said.The story told by Givens held for many others in Texas towns inundated by days of torrential rains, with highways still submerged and homes destroyed.A hospital in the hard-hit town of Beaumont was forced to evacuate its patients - nearly 200 people - when the town's water s Once upon a time in Europe, pregnant women avoided rabbits to prevent their babies from being born with a “harelip.” But, that apparently isn’t the only misconception about the condition now known as cleft lip.In the May 1 issue of Cell Reports, UConn Health resear chers report the popular modern belief that the condition is caused by a gene is, in fact, not the case at all.Their research could transform how we understand the formation of the face.Cl efts of the mouth and face affect up to 1 in 500 people, making it one of the most common birth defects. Sometimes the cleft is j ust a small indentation of a person’s lip, while in other cases the cleft splits deeply into the lip, upper palate and even the nose. And most of the time, a person with a cleft has no other malformations of the bones or other organs.A few genes have been associated with facial clefts, but they account for only a very small number of cases.“They’re not like other disorders caused by mutation in a gene. Generally th
Jlfz Genetic Atlases Reveal New Landscapes in Brain Structure DIYARBAKIR:Explosives planted by Kurdistan Workers Party (PKK) militants ripped through a Turkish military vehicle traveling through southeast Turkey on Monday, wounding 17 soldiers, the military said.The vehicle was passing through the Yuksekova district of Hakkari province, which borders Iran and Iraq, when the blast occurred, the army said, adding the wounded were immediately taken to hospital.Choose Turkey or terrorists, Erdogan tells WestThe army initially said four of the wounded were in a serious condition, but a later statement said none of the injuries were serious.The PKK took up arms against the Turkish state in 1984 and more than 40,000 people, mostly Kurds, have been killed in the conflict. It is designated a terrorist group by Turkey, the United States and the European Union.Muslim countries can contribute towards global peace : ErdoganA ceasefire between the Turkish state and the mil itants broke down in July 2015 and the southeast subsequently saw some of the worst violen Thermo Fisher Scientific has announced the official opening of its new GMP1 standard facility in South Korea. Strategically located in Seoul, the new site will provide local, regional and global pharmaceutical and biotech companies with a one-stop service for clinical supplies − from cGMP storage, local labelling, secondary packaging, comparator sourcing, handling and distribution of ambient and cold chain supplies to clinical site returns management.A supportive government, modern infrastructure and an easily accessible patient population are helping this Asian nation bec ome a top location for clinical trial research. Over the past few years, clinical trials have consistently grown in South Korea, and with an increased number of core clinical trial sites certified by the Ministry of Food and Drug Safety (MFDS), formerly known as the KFDA, South Korea boasts the second highest number of approved clinic al trial sites globally, making it a leading emerging nation for clinical trial resea
Hjgz The declining trend in Pakistan s exports Pakistan fast-bowler Wahab Riaz has hailed the influence of new coach Mickey Arthur, who according to him has instilled a “fearless” approach to Pakistan’s limited-over cricket.Arthur took over from former coach Waqar Younis, who stepped down after the team’s dismal performance in the World T 20 this year.In his first real assignment as the team’s coach, Arthur’s men secured a historic draw in the Test series in England, which eventually helped the Green Caps to reach the top spot in the longest format of the game.Umar, Shafiq recalled to Pakistan ODI sideHowever, the team suffered a humiliating 4-1 defeat in the ODI series against England, after whi ch the coach said that there is no place for underperforming players in the team.Wahab said that Arthur is focused on the efforts of the players, which is what all he demands from the team. “What [Arthur] requires is the effort, which I would say is the main thing he has brought,” Wahab was quoted by Sports360. “I think that’s the big differ An international team of scientists have confi rmed the discovery of a major cause of dementia, with important implications for possible treatment and diagnosis.Professor Garth Cooper from The University of Manchester, who leads the Manchester team, says the build-up of urea in the brain to toxic levels can cause brain damage – and eventually dementia.The work follows on from Professor Cooper’s earlier studies, which identified metabolic linkages between Huntington’s, other neurodegenerative diseases and type-2 diabetes.The team consists of scientists from The University of Manchester, the University of Auckland, AgResearch New Zealand, the South Australian Research and Development Institute, Massachusetts General Hospital and Harva rd University.The latest paper by the scientists, published today in the Proceedings of the National Academy of Sciences, shows that Huntington’s Disease - one of seven major types of age-related dementia - is directly linked to brain urea levels and metaboli
Lxtd Underutilised budgets ISLAMABAD:The Aabpara police on Tuesday arrested a man and seized weapons and ammunition from his possession.The police intercepted Abdul Rasheed at Zero Point and seized a 9mm pistol, two magazines and six bullets during his vehicle search. The police have registered a case against him and started investigation.Published in The Express T ribune, May 11th, 2016. In blind people, brain's vision center plays role in solving math problems - Human babies and even animals have a basic number sense that many believe evolves from seeing the world and trying to quantify all the sights. But vision has nothing to do with it—Johns Hopkins Universi ty (JHU) neuroscientists have found that the brain network behind numerical reasoning is identical in blind and sighted people .See Also: An eye opening look at adult visual plasticityThe researchers also found the visual cortex in blind people is highly involved in doing math, suggesting the brain is vastly more adaptable than previously believed. The findings are published in the journal Proceedings of the National Academy of Sciences."The number network develops totally i ndependently of visual experience," said lead author Shipra Kanjlia, a graduate student in JHU's Department of Psychological and Brain Sciences. "These blind people have never seen anything in their lives, but they
Usyi Physicists Decode Decision Circuit of Cancer Metastasis India plans to deport nearly 10, 000 Rohingya Muslims from Indian-held Kashmir, the Intern ational Business Times reported.The decision, based on a proposal by the Indian government in occupied Kashmir, was made following a high-level meeting by the central government – it was endorsed by both the state and federal government, who are working on implementing it."The Ministry is exploring ways and means to identify and deport the Rohingya Muslims from the State," the New Indian Express quoted a Union Home Ministry official after the meet.For persecuted Rohingya Muslims, a place to call home in IndiaThe newspaper further claims the Rohingyas Muslims are accused of raising funds for militant activities through drug trafficking and smuggling by the country’s intelligence services.Between 5, 000 – 10, 000 Rohingya Muslims reportedly entered Indian-occupied Kashmir illegally through Indo-Bangladesh and Indo-Myanmar border. Currently an estimated 40, 000 are believed to be living as “illegal s Assessing the patterns of energy use and neuronal activity simultaneou sly in the human brain improves our understanding of how alcohol affects the brain, according to new research by scientists at the National Institutes of Health. The new approach for characterizing brain energetic patterns could also be useful for studying other neuropsychiatric diseases. A report of the findings is now online in Nature Communications.“The brain uses a lot of energy compared to other body organs, and the association between brain activity and energy utilization is an important marker of brain health,” said George F. Koob, Ph.D., director of the National Institute on Alcohol Abuse and Alcoholism (NIAAA), part of NIH, which funded the study. “This study intr oduces a new way of characterizing how brain activity is related to its consumption of glucose, which could be very useful in understanding how the brain uses energy in health and disease.”The research was led by Dr. Ehsan Shokri-Kojori and Dr. Nora
Gkqc Man breaks into US mosque, tears apart copies of Holy Quran PESHAWAR:The issue of eleven hardcore terrorists, including an Afghan citizen, who escaped from Mardan Police Lines two months ago, has been brushed under the carpet by the provincial government and law-enforcement agencies. The suspects have yet to be taken back into custody.The names of those who reportedly escaped were obtained by The Express Tribune from official sources. They include Muhammad Gul alias Ahmad. He is a resident of Afghanistan. Others on the list ar e Gul Muhammad Umer Bajwri and Nihar Ali.Akhtar Iqbal, Majid Ali, Muhammad Ali, alias Yasin, Abdullah alias Hamza, Muhammad Israil alias Muhammada, Akhter alias Khan Ghi, Arshad alias Pir Saib, and Muhammad Suleman alias Ahmad are also on the list.Sources said a constable of the Mardan police was involved in the episode, but the enquiry against him has been shelved. Intelligence agencies issued a warrant for the escaped militants and termed them a danger to peace and stability in the region.Published in The Express Tribune Agilent Technologies Inc. announced it will kick off its Young Scientist Forum series in Asia on March 28 for emerging talents in the biomedical and life science industries. Young scientists at the Agilent-organized events, to be held in Australia and Singapore, will be able to interact, share ideas and network with senior scientists.Experienced scientists and researchers who have worked closely with Agilent for many years will serve as hosts and mentors to facilitate the exchange of ideas with emerging talents. The young scientists will have the opportunity to present their work, engage in discussions with their mentors, and gain insights into building their careers in the dynamic life science indus try. The forum will boost their knowledge across various disciplines such as genomics, proteomics and metabolomics."As a technology partner to the research community, it is important that Agilent nurtures tomorrow's upcoming scientists and researchers," said A gilent's Rod Minett, general ma
Bxni The cut: Unforgettable looks of the week! LAHORE:Receivables of independent power producers (IPPs) and other electricity producers have once again swelled and the figure has now reached Rs439 billion, raising the spectre of another hard-hitting summer for power consumers.The current government, s oon after coming to power in mid-2013, cleared Rs480 billion worth of circular debt, but after almost four years, the debt pile has again grown to around the same level, meaning the pa yment structure has not been streamlined yet.According to official documents, pending payments to the power producers, including IPPs, reached Rs439 billion on February 15, 2017.The high receivables may compound consumer woes in coming days as winter has come to an end and the government has failed to clear outstanding dues of 57 power companies.Statistics show Kot Addu Power Company is to receive Rs6.82 billion, Hub Power Company is to get Rs6.4 billion, Central Power Generation Company Rs6.28 billion, Northern Power Generation Company Rs5.67 billion, Wa Neuroscien tists from the University of Vienna and the Karolinska Institute in Stockholm have investigated whether playing violent video games leads to a reduction in human empathy. To do this, they had adult test subjects play a violent video game repeatedly over the course of an experiment lasting several weeks. Before and after, their empathic responses to the pain of another person were measured. It was found that the violent video game had no discernible effect on empat hy and underlying brain activity. These results have now been published in the renowned journaleLife.Video games have become an integral part of the everyday life of many children and adults. Many of the most popular video games contain explicit depictions of extreme violence. Therefore, concerns have been raised that these games may blunt the empathy of their players and could therefore lower the inhibition threshold for real violence. An international research team led by Viennese neuroscientists Claus Lamm and Luk
Jckq Nanogen Gains Access to Schizophrenia Markers KARACHI:Asghar Imam, a 54-year-old father of eight, who was wounded during a clash on Sunday between protesting residents of Orangi Town and police, succumbed to his injuries during treatment at a hospital on Monday.He was wounded during the three-hour-long clash between protesters and police near his residence at Islam Chowk. He was shot o nce in his back during the protest a nd admitted to Abbasi Shaheed Hospital where he succumbed to his injuries. Three others were admitted at the hospital but doctors said they were out of danger. In a video that went viral on social media, police personnel could be seen opening fire at the protesters and a policeman could also be heard forcing a fellow cop to shoot at the protesters' heads.Imam's family claimed that his death is proof that the police opened fire at the protesters. "Are we living in Kashmir where police open fire at protesters?" questioned Imam's relative Ghayyasuddin.Zone West police chief DIG Zulfiqar Larik told the media that there Dopamine rgic neurons & decision making; how animals see the world; transforming skin cells into neurons, and more.♦ The role of dopaminergi c neurons in decision makingA crucial element for the survival of animals and humans is learning how to acquire rewarding stimuli—food, sex, and social rewards. While learning is powerful skill, nothing in the world remains the same for long, and learning must be adaptive in order to allow an animal to flexibly survive a changing environment. Dopamine has long been known for its critical role in cue-reward associations, and new data provide a mu ch richer and complex image of how dopaminergic neurons function.♦ Why it's hard to make a bunny mad: Examining prion disease resistance in rabbits Rabbits have long been considered immune to prion disease, but recently scientists have shown that they can--under certain circumstances--get transmissible spongiform encephalopathy (TSE). Two studies published in PLOS Pathogens address w
Maxr Hormone Helps To Prevent Muscle Loss in Mice Fed High Fat Diets KARACHI:Pakistan’s social entrepreneurship eco-system still requires dedicated investors and knowledge base to grow socially responsible businesses and contribute to youth employment. This was the main focus of speakers at the University town hall on “Social Entrepreneurship: Breaking Glass Ceilings” held at the Karachi School of Business and Leadership on Thursday by KSBL and Jinnah Institute. Speaking on the occasion, KSBL Registar Dr Iqbal Tahir spoke about the success and salient features of KSBL’s MBA program and shared the vision of KSBL to become the leading business school in Pakistan. Starting the dialogue, Nadeem Hussain said that socially sustainable enterprises in Pakistan still need strengthening of the eco-system, investors and mentors to support young men and women who want to start businesses targeting service provision for the poor in Pakistan.Published in The Express Tribune, October 2nd, 2016.Like Business on מנא מנא תקל ופרסין , f ollow @TribuneBiz on Twitter to stay informed Vitamin D plays an integ ral role in regulating immune function, and Penn State researchers have identified immune cells in mice that can be differentiated by whether or not they have vitamin D receptors — a finding that could lead to a better understanding of the link between vitamin D status and autoimmune diseases such as ulcerative colitis, Crohn’s disease and multiple sclerosis.In laboratory studies, Margherita Cantorna, distinguished professor of molecular immunology in the College of Agricultural Sciences, an d Juhi Arora, former pathobiology doctoral student in the Cantorna lab, used flow cytometry, a lab test that analyzes characteristics of cells or particles, to perform highly sensitive assays or analyses to determine the composition of substances. These assays categorized particular immune cells based on whether or not they express the vitamin D receptor. Immune cells include cells such as monocytes, T cells and B cells — all of which perform critical roles in the immune syst
Ltqr Academics celebrate Washington Accord membership PARIS:The Eiffel Tower reopened to the public on Sunday after a labour strike closed the Paris landmark for five days.Members of the 300-strong workforce voted Sunday to resume their duties following a dispute over management's decision-making and maintenance work, the CGT union said.Eiffel Tower shut by third strike of 2016Unions and management are to sign a memorandum of understanding, the union said, without disclosing its contents.During the C hristmas rush as many as 20,000 people a day ascend the tower.Eiffel Tower to go dark in solidarity with people of AleppoAmong t he projects that workers are concerned about are a major paint-stripping and repainting job to repair flaking areas of the 117-year-old tower which unions say poses health risks because of lead in the old paint. GenISys GmbH, a provider of software for optimization of microstructure fabrication processes, has announced it has signed an agreement with theFraunhofer Institute of Integrated Systems and Device Technology (IISB) for the development and licensing of advanced 3-D resist modeling techniques for e-beam and proximity lithography.GenISys further announced that Nikola Belic, a pioneer in proximity effect correction (PEC) technology and developer of the widely used Proxecco PEC software, will join GenISys as senior d evelopment engineer, effective January 2 008.According to the terms of its agreement with Fraunhofer IISB, GenISys will integrate the 3-D resist modeling technologies developed by Fraunhofer IISB’s Lithography Simulation Group under the direction of Dr. Andreas Erdman into GenISys’ products for proximity lithography for microsystems and e-beam lithography, and market them.Insofar, GenISys wi ll be the sole software house partner for IISB regarding distribution. Specifically, GenI
Nzdg Could exercise help meth addicts recover Circadian rhythms are key, study finds Karachi Kings' Chris Gayle, Kumar Sangakkara and Mahela Jayawardene have refused to travel to Lahore for the Pakistan Super League (PSL) final despite being made lucrative financial offers by the league organisers.As m any as 50 cricketers expressed their desire to partake in the title-deciding match after the PSL organis ers, following a high-level meeting, decided to go ahead and hold the match in Lahore, per Express NewsHowever, absent from the list was the star trio of Gayle, Sangakkara and Jayawardene, who have refused to travel to Pakistan, citing the country's volatile security conditions.Babar-ic Azam gifts Karachi first win in PSL2The PCB, in order to bring international players on board, has reportedly offered between $10,000 and $50,000 to the said players on top of the salaries they are already receiving. Human cytomegalovirus is a leading cause of birth defects and transplant failures.As it has evolved over time, this virus from the herpes family has found a way to bypass the body’s defence mechanisms that usually guards against viral infections. Until now, scientists couldn’t understand how it manages to do so.A team of scientists led by Leor S. Weinberger, PhD, the William and Ute Bowes Distinguished Professor and director of the Gladstone–UCSF Center for Cell Circuitry, uncovered the mechanism that allows the virus to replicate. Their study, published in the scientific journal PNAS, could open new therapeutic avenues to treat not only cytomegalov irus, but other viruses as well.Normally, when a virus enters your cell, that cell blocks the virus’s DNA and prev ents it from performing any actions. The virus must overcome this barrier to effectively multiply.To get around this obstacle, cytomegalovirus doesn’t simply inject its own DNA into a human cell. Instead, it carries its viral DNA
Jdjq BioGenes Has Developed Cellmid s Midkine Blood Test and Reports Manufacture of First Kits LAHORE:Sufficient stocks of sugar are available in the country and the recent increase in prices of the commodity is due to the market mechanism, said a spokesman for the Pakistan Su gar Mills Association Punjab Zone. “When payments of sugarcane growers are cleared every year, the pressure of sales on sugar mills decreases due to which fluctuation in sugar prices is a normal phenomenon,” th e spokesman stated. Owing to continued increase in sugarcane prices, the cost of sugar production had increased considerably, which stood at Rs64 to Rs65 per kg ex-mill, he said, adding if the mark-up of March-July was taken into account, then the ex-mill price should be Rs66 to Rs67 per kg. He insisted that there was no contraction in the supply of sugar however, sometimes middlemen would try to exploit the situation.Published in The Express Tribune, July 29th, 2016.Like Business on מנא מנא תקל ופרסין , follow @TribuneBiz on Twitter to stay informed and join in the conversation. An FDA-approved drug for hepatitis C can increase bacterial sensitivity to antibiotics and reduce the likelihood of antibiotic resistance, according to a new study led by New York University researchers published inCell Chemical Biology. The drug called telaprevir works by blocking the function of chaperones—important proteins that fold other proteins in the cell—in bacteria. “Telaprevir is the first previously clinically approved compound that has been shown to inhibit chaperone function in bacteria,” said Tania Lupoli, assistant professor of chemistry at NYU and the study’s senior author. “Our research marks a vi tal step in developing small molecule chaperone inhibitors that can be used in bacteria to increase the power of antibiotics and slow down the evolution of antibiotic resistance.”Chaperones exist in almost every cell in every organism, from single-cell bact eria to humans. Due to their critical role in folding other proteins—and what happens when proteins misfold, which can le
Xxbf Trump asked Comey to end investigation of Michael Flynn: source ISLAMABAD:Imran K han should stop th reatening and bullying the constitutional institutions, said State Minister for Information, Broadcasting and Nationa l Heritage Marriyum Aurangzeb on Tuesday. In a statement, the minister termed Imran Khan and the PTI’s campaign against the superior judiciary as regrettable. The minister said that Imran should know that he and his party would face the test of voters in the 2018 elections. She said that Imran has not done anything during the past three and a half years, apart from lying.Published in The Express Tribune, December 14th, 2016. Skoltech researchers and their colleagues from Russia, Germany, and the U.S. have found Prozac to reduce lipid concentrations in juvenile macaques who received the antidepressant for two years, compared toacontrol group of untreated animals. While none of the monkeys in the study were depressed, thefindings still offer a plausible biochemical explanation for the drug’s side effects, particularly in young patients. Thepaper was published in the International Journal of Molecular Sciences.Prozac is the most widely prescribed antidepressant in the world and is approved in the United States fortreating children as young as 8 years old with major depressive disorder and 7 years old with obsessive-compulsive disorder. There is a certain amount of controversy surrounding this use, with some studies claiming the drug might actually increase the likelihood of suicidal thinking and behaviour and that this side effect could be more pronounced in young patients. This makes biochemical research into
Ipjt Illumina Infinium BeadChips Selected by Germany s National Genome Research Network MOS COW:Hosts Russia kick off the Confederations Cup against New Zealand in Saint Petersburg on Saturday, targeting victory in their opening match to set the tone for a successful tournament."We've worked hard and I believe now we're well-prepared for the opening game," Zenit midfielder Igor Smolnikov told Russian TV. "But we will be able to check whether we've done everything right only once we play in official matches.”Smolnikov believes hosts will go in to the tournament with full of optimism. "We're all feeling brave and will take things on full of optimism. Hopefully, the arena in Saint Pet ersburg will be a lucky venue for our team."World Cup winners Lahm, Alonso’s final hurrahRussian President Vladimir Putin will attend the opener along with FIFA boss Gianni Infantino at Saint Petersburg's purpose-built World Cup 68,000-seater stadium.It w ill be the first meeting between Russia and New Zealand, the champions of Oceania, in the post-Soviet era. The USSR beat New Zealand 3-0 at the Valneva SE (Valneva) has announced the completion of the merger of equals between Vivalis and Intercell, creating a new European biotech company focusing on vacc ines and antibodies, striving to become a leader in its field.Valneva ordinary shares (ISIN FR0004056851) start trading on the regulated market of NYSE Euronext in Paris under the ticker symbol “VLA.PA” and on the Prime Market segment of the Vienna Stock Exchange under the ticker symbol “VLA”.Valneva preferred shares (ISIN FR0011472943) will start trading on the regulat ed market of NYSE Euronext in Paris under ticker symbol “VLApr.PA” and on the unregulated Third Market Segment of the Vienna Stock Exchange under the ticker symbol “VLAP”.Thomas Lingelbach, President and Chief Executive Officer and Franck Grimaud, President and Chief Business Officer of Valneva, commented: “Today is a major milestone for our new company. Valneva combines the strengths and capabilities of Vivalis and Intercell in antibody discovery and vaccine dev
Fwsq BioNano Genomics, Berry Genomics Collaborate ISLAMABAD:Opera and Sufi music both enjoy long traditions in their respective regions. One in the west and the other in the east.It is thus fitting that the person bringing these two genres of music together is someone who hails from the east but was raised in the west.Saira Peter, a Briton of Pakistani origin and an opera singer, gave a full account of not only her talents but also of a successful integration of the eastern Sufi music with that of western classical opera at the at the Pakistan National Council of the Arts (PNCA) auditorium on Friday.Celebrating Sufism and promoting the message of peaceShe beautifully fused western and eastern music, skillfully singing her opera-infused renditions of popular Sufi Punjabi texts. Peter also presented popular songs such as ‘Mere Dholna’, ‘Awaz dey kahan hu’ Khawaja Meray Khawaja, Teray Mast Ma st and other songs, as she showcased her unique combinati ons of opera music with the teachings of Sufism.Singing live, Peter mesmerised the audience There is never a "right" time to have a baby, so the saying goes. T here is a myriad of factors to take into consideration when deciding to have a child, which might include financial stability, personal goals and aspirations or accessibility to childcare support. The list goes on and is unique and deeply personal."For many people, the question of whether to have children or not is one of the biggest they will face in their lives," Sabrina Helm, associate professor in the Norton School of Fam ily and Consumer Sciences at the University of Arizona, said in a press release.Helm is the lead author of a new study published in Population and Environment that sought to discover whether climate change was a concern that impacted individuals' decisions to have a child.1 "As public concern about climate change grows, anecdotal evidence reported in the media points to a group of people who are questioning their fertility desires and intentions," the researchers write in the paper.A two-pronged app
Jtug Corporate results: Silkbank posts Rs1.7b loss in 2015 HMD Global, the Finnish start-up looking to reinvigorate the Nokia phone brand, unveiled the Nokia 8 on Wednes day, hoping to cash in on rising consumer demand for high-quality audio and video features.The Android device, due out in September, will potentially beat rivals on price but will still face fierce competition, with Apple's highly anticipated 10th anniversary iPhone also expected next month and Samsung's Galaxy Note 8 set to hit the market next week.With a suggested price tag of around 599 euros ($703), the Nokia 8 undercuts Appl e, which typically offers a stripped down version of its latest phones for a similar price but charges hundreds of euros more for memory and key features.Nokia ready for smartphone comeback in 2017The new top-of-the-line Nokia sports a dual-sight video feature which enables simultaneous live-streaming on social media networks from both front and rear cameras on a split screen. It has licensed lens technology from camera maker Zeis s.It is the most high-e A charity-industry collaboration has launched an initiative to find new epigenetic drug treatments to improve th e lives of millions of people affected by respiratory diseases every year.The respiratory collaboration brings MRC Technology, Asthma UK, AstraZeneca, and the British Lung Foundation together to investigate the link between epigenetics and respiratory disease. Epigenetics are changes in the expression of genes, which could be attributed to lifestyle and other external factors affecting the body. Epigenetics do not change the DNA sequence. Until now epigenetics research has mostly focused on cancer, but it presents a promising avenue for respiratory research which, it is hoped, will help speed up the delivery of new treatments. The collaboration is combining resources and expertise in drug discovery and clinical development, funding, and access to research networks and patient groups to enable early stage scientific research to be translated into potential new therapies for re
